Cleanse face and pat dry. Remove syringe cap and apply entire contents onto face. Massage for 1-2 minutes, using circular motions, followed by light tapping. Tear open Bio-Cellulose mask sachet. Remove both protective layers and discard. Apply mask on skin for 20 minutes. Remove and discard. Gently massage in remaining serum and leave on overnight for best results. Use 2-3 times a month.